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EPH Receptor A2 抗体 (N-Term)

This anti-EPH Receptor A2 antibody is a 兔 多克隆 antibody detecting EPH Receptor A2 in WB, FACS 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN391885
发货至: 中国

Quick Overview for EPH Receptor A2 抗体 (N-Term) (ABIN391885)

抗原

See all EPH Receptor A2 (EPHA2) 抗体
EPH Receptor A2 (EPHA2)

适用

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人, 小鼠

宿主

  • 111
  • 17
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克隆类型

  • 107
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  • 1
多克隆

标记

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This EPH Receptor A2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB01579
  • 抗原表位

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    AA 30-60, N-Term

    预测反应

    Pr

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This EphA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-60 amino acids from the N-terminal region of human EphA2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Tatsukawa, Koga, Aoki, Koshikawa, Imafuku, Nakayama, Nabeshima: "Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma." in: Virchows Archiv : an international journal of pathology, Vol. 469, Issue 1, pp. 25-34, (2017) (PubMed).

  • 抗原

    EPH Receptor A2 (EPHA2)

    别名

    EphA2

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

    分子量

    108266

    基因ID

    1969

    NCBI登录号

    NP_004422

    UniProt

    P29317

    途径

    RTK signaling
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