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LKB1 抗体 (N-Term)

Cited in 1 publication. This anti-LKB1 antibody is a 兔 多克隆 antibody detecting LKB1 in WB, IF, IHC (p) 和 FACS. Suitable for 人.
产品编号 ABIN391350
发货至: 中国
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Quick Overview for LKB1 抗体 (N-Term) (ABIN391350)

抗原

See all LKB1 (STK11) 抗体
LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

适用

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宿主

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克隆类型

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多克隆

标记

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This LKB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB3547
  • 抗原表位

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    AA 14-44, N-Term

    预测反应

    C, M, Rat, X

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human STK11 (LKB1).

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

    有效期

    6 months
  • Sohn, Jang, Campan, Weisenberger, Dickhout, Wang, Cho, Yates, Lucock, Chiang, Austin, Choi, Laird, Kim et al.: "The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer ..." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 1999-2005, (2009) (PubMed).

  • 抗原

    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

    别名

    STK11 (LKB1)

    背景

    STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

    分子量

    48636

    NCBI登录号

    NP_000446

    UniProt

    Q15831

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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