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MSK2 抗体 (C-Term)

This anti-MSK2 antibody is a 兔 多克隆 antibody detecting MSK2 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN390994
发货至: 中国

Quick Overview for MSK2 抗体 (C-Term) (ABIN390994)

抗原

See all MSK2 (RPS6KA4) 抗体
MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))

适用

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人, 小鼠

宿主

  • 40
  • 2

克隆类型

  • 40
  • 2
多克隆

标记

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This MSK2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB1020
  • 抗原表位

    • 10
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    • 1
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    AA 322-354, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This RSKB (MSK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-354 amino acids from the C-terminal region of human RSKB (MSK2).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Lee, McCool, Murdoch, Fritsch et al.: "Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK ..." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 21162-72, (2006) (PubMed).

  • 抗原

    MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))

    别名

    RSKB (MSK2)

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK). The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).

    分子量

    85606

    基因ID

    8986

    NCBI登录号

    NP_001006945, NP_003933

    UniProt

    O75676
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