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TAB1 抗体 (AA 416-445)

TAB1 适用: 人 WB 宿主: 兔 Polyclonal RB12875 unconjugated
产品编号 ABIN390847
发货至: 中国
  • 抗原 See all TAB1 抗体
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    抗原表位
    • 15
    • 15
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 416-445
    适用
    • 93
    • 41
    • 28
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 97
    • 9
    • 2
    克隆类型
    • 100
    • 8
    多克隆
    标记
    • 41
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This TAB1 antibody is un-conjugated
    应用范围
    • 69
    • 48
    • 26
    • 26
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB)
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MAP3K7IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-445 amino acids from human MAP3K7IP1.
    克隆位点
    RB12875
    亚型
    Ig Fraction
    Top Product
    Discover our top product TAB1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
    别名
    MAP3K7IP1 (TAB1 产品)
    别名
    3'-Tab1 antibody, MAP3K7IP1 antibody, 2310012M03Rik antibody, Map3k7ip1 antibody, b2b449Clo antibody, TGF-beta activated kinase 1 (MAP3K7) binding protein 1 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 1 antibody, TAB1 antibody, Tab1 antibody
    背景
    MAP3K7IP1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli.
    分子量
    54644
    基因ID
    10454
    NCBI登录号
    NP_006107, NP_705717
    UniProt
    Q15750
    途径
    TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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