电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PINK1 抗体 (N-Term)

This anti-PINK1 antibody is a 兔 多克隆 antibody detecting PINK1 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN390369
发货至: 中国

Quick Overview for PINK1 抗体 (N-Term) (ABIN390369)

抗原

See all PINK1 抗体
PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

适用

  • 89
  • 29
  • 10
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 57
  • 44
  • 1

克隆类型

  • 61
  • 43
多克隆

标记

  • 58
  • 8
  • 6
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PINK1 antibody is un-conjugated

应用范围

  • 77
  • 62
  • 44
  • 28
  • 20
  • 8
  • 6
  • 5
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB07381
  • 抗原表位

    • 28
    • 8
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 118-147, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the N-terminal region of human PINK1 (PARK6).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Wang, Hu, Zou, Xiang, Jiang, Botchway, Huo, Du, Fang: "The post-therapeutic effect of rapamycin in mild traumatic brain-injured rats ensuing in the upregulation of autophagy and mitophagy." in: Cell biology international, Vol. 41, Issue 9, pp. 1039-1047, (2018) (PubMed).

    Zhang, Gu, Chen, Ni, Hung, Wang, Zhang, Feng, Ji: "High expression of PINK1 promotes proliferation and chemoresistance of NSCLC." in: Oncology reports, Vol. 37, Issue 4, pp. 2137-2146, (2017) (PubMed).

  • 抗原

    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

    别名

    PINK1 (PARK6)

    背景

    Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.

    分子量

    62769

    基因ID

    65018

    NCBI登录号

    NP_115785

    UniProt

    Q9BXM7

    途径

    Autophagy
You are here:
Chat with us!