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MTOR 抗体 (AA 2459-2488)

Name: MTOR 抗体 (AA 2459-2488)
SKU: ABIN390217
Availability: OutOfStock

Cited in 3+ publications. This 兔多克隆 anti-MTOR antibody (Clone RB13347) specifically detects MTOR in WB, IF 和 IHC (p). The antibody is reactive with 人 samples.

All lanes : Anti-FR Antibody (p) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 μg per lane. (MTOR 抗体 (AA 2459-2488))

Formalin-fixed and paraffin-embedded human testis tissue reacted with FRp, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MTOR 抗体 (AA 2459-2488))

IHC (p)

Confocal immunofluorescent analysis of mTOR (FR) Antibody (ABIN390217 and ABIN2840698) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (MTOR 抗体 (AA 2459-2488))

Western blot analysis of FR (arrow) using rabbit polyclonal FR Antibody (ABIN390217 and ABIN2840698). (MTOR 抗体 (AA 2459-2488))

4 images

(3 references)

产品编号 ABIN390217

发货至: 中国

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中国
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Quick Overview for MTOR 抗体 (AA 2459-2488) (ABIN390217)

抗原

See all MTOR (mTOR) 抗体

MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MTOR antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB13347

Discover our top product mTOR Primary Antibody

抗原表位
38

37

22

15

11

10

5

5

4

4

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2459-2488

预测反应

M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This mTOR (FRAP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2459-2488 amino acids from human mTOR (FRAP1).

亚型

Ig Fraction
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2436-2492) antibody
mTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (C-Term) antibody
mTOR 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2226-2488) antibody
mTOR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2400-2500) antibody
mTOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (pSer2448) antibody
KD Validated mTOR 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 24GB330 unconjugated Recombinant Antibody

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) antibody
mTOR 适用: 人, 小鼠, 大鼠, 鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2311-2529) antibody
mTOR 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8H5A5 unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) antibody
KD Validated mTOR 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB200 unconjugated Recombinant Antibody

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (pSer2481) antibody
mTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (pSer2448) antibody
mTOR 适用: 人, 小鼠, 大鼠, Cow, 鱼 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Yang, Cheng, Zhou, Zhu, Hu, Yang: "Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma." in: International journal of molecular sciences, Vol. 16, Issue 12, pp. 28635-46, (2016) (PubMed).

Liu, Wu, Huang: "Orientin protects myocardial cells against hypoxia-reoxygenation injury through induction of autophagy." in: European journal of pharmacology, Vol. 776, pp. 90-8, (2016) (PubMed).

Cao, Dong, Meng, Liu, Liao, Liu: "MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3." in: Tumour biology, Vol. 36, Issue 6, pp. 4453-9, (2015) (PubMed).
抗原

MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

别名

mTOR (FRAP1)

背景

FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.

分子量

288892

基因ID

2475

NCBI登录号

NP_004949

UniProt

P42345

途径

PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect