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NOTCH3 抗体 (C-Term)

This anti-NOTCH3 antibody is a 兔 多克隆 antibody detecting NOTCH3 in WB, IF 和 IHC (p). Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN390159
发货至: 中国

Quick Overview for NOTCH3 抗体 (C-Term) (ABIN390159)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

  • 57
  • 18
  • 11
  • 1
小鼠

宿主

  • 42
  • 16
  • 3
  • 1
  • 1

克隆类型

  • 46
  • 18
多克隆

标记

  • 33
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This NOTCH3 antibody is un-conjugated

应用范围

  • 27
  • 25
  • 23
  • 8
  • 6
  • 5
  • 5
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB02199
  • 抗原表位

    • 12
    • 10
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 2291-2321, C-Term

    预测反应

    H

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This NOTCH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Liu, Yang, Wang, Miao, Liu, Li, Zou, Li, Liang, Zeng, Chen: "The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance." in: Pathology oncology research : POR, Vol. 22, Issue 3, pp. 483-92, (2017) (PubMed).

  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    NOTCH3

    背景

    NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

    分子量

    243631

    基因ID

    4854

    NCBI登录号

    NP_000426

    UniProt

    Q9UM47

    途径

    Notch Signaling
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