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BIRC3 抗体 (N-Term)

Cited in 2+ publications. This anti-BIRC3 antibody is a 兔 多克隆 antibody detecting BIRC3 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN390069
发货至: 中国
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Quick Overview for BIRC3 抗体 (N-Term) (ABIN390069)

抗原

See all BIRC3 抗体
BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

适用

  • 60
  • 22
  • 5
  • 2

宿主

  • 53
  • 7
  • 1

克隆类型

  • 54
  • 7
多克隆

标记

  • 34
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BIRC3 antibody is un-conjugated

应用范围

  • 49
  • 27
  • 22
  • 13
  • 13
  • 11
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB2213
  • 抗原表位

    • 15
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-131, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This cIAP2 (BIRC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-131 amino acids from the N-terminal region of human cIAP2 (BIRC3).

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Chen, Xie, Gu, Cai, Wang, Xie, Dong, He, Zhong, Lin, Huang: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).

    Sun, Liu, Zou, Lan, Sun, Wang, Zhao, Jiang, Liu: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).

  • 抗原

    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

    别名

    cIAP2 (BIRC3)

    背景

    BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.

    分子量

    68372

    基因ID

    330

    NCBI登录号

    NP_001156, NP_892007

    UniProt

    Q13489

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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