电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Insulin Receptor 抗体 (pTyr1185)

This anti-Insulin Receptor antibody is a 兔 多克隆 antibody detecting Insulin Receptor in DB. Suitable for 人.
产品编号 ABIN389937
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (pTyr1185) (ABIN389937)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

  • 175
  • 92
  • 82
  • 16
  • 13
  • 8
  • 7
  • 6
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 164
  • 31
  • 2
  • 1

克隆类型

  • 150
  • 48
多克隆

标记

  • 128
  • 17
  • 15
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Insulin Receptor antibody is un-conjugated

应用范围

  • 146
  • 78
  • 63
  • 36
  • 25
  • 22
  • 19
  • 15
  • 13
  • 13
  • 8
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dot Blot (DB)

克隆位点

RB15377
  • 抗原表位

    • 16
    • 14
    • 13
    • 10
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1185

    预测反应

    B, M, Rat, X, D

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This INSR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1185 of human INSR.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR

    背景

    Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake, thereby mediating the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). This protein can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked.

    分子量

    156333

    基因ID

    3643

    NCBI登录号

    NP_000199, NP_001073285

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
You are here:
Chat with us!