FEN1 抗体 (AA 243-272)
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北京 101111
Quick Overview for FEN1 抗体 (AA 243-272) (ABIN389376)
抗原
See all FEN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 243-272
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预测反应
- B, Sh
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This FEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the Central region of human FEN1.
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亚型
- Ig Fraction
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anti-Flap Structure-Specific Endonuclease 1 (FEN1) (AA 50-380) antibody
FEN1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC, IF, IP, IHC (p), ICC, PLA 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 4D9 unconjugated Recombinant Antibody
anti-Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) antibodyFEN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) (Internal Region) antibodyFEN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- IF: 1:100. WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
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别名
- FEN1
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背景
- FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. This protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.
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分子量
- 42593
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基因ID
- 2237
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NCBI登录号
- NP_004102
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UniProt
- P39748
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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