PPT1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for PPT1 抗体 (N-Term) (ABIN389116)
抗原
See all PPT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 32-63, N-Term
-
预测反应
- B, Pr
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-63 amino acids from the N-terminal region of human PPT1.
-
亚型
- Ig Fraction
-
-
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 100-306) antibody
PPT1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 1-306) antibodyPPT1 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1117CT11-2-1-4 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) antibodyPPT1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 10G4 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 1-306) antibodyPPT1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 100-306) antibodyPPT1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 188-290) antibodyPPT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 28-279) antibodyPPT1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 100-258) antibodyPPT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 191-224), (C-Term) antibodyPPT1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (AA 269-300), (C-Term) antibodyPPT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4707 unconjugated
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))
-
别名
- PPT1
-
背景
- Palmitoyl-protein thioesterase-1 (PPT1) is a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mutations in PPT1 have been found to cause the infantile form of neuronal ceroid lipofuscinosis (INCL), and an animal model has been developed.1 The deduced PPT2 protein contains 302 amino acids, including a 27-amino acid leader peptide, a sequence motif characteristic of many thioesterases and lipases, and 5 potential N-linked glycosylation sites.2 PPT2 shares 18 % amino acid identity with PPT1. Northern blot analysis detected a predominant 2.0-kb PPT2 transcript in the human tissues examined, with the highest expression in skeletal muscle, variable amounts of 2.8- and 7.0-kb transcripts were also observed. Recombinant PPT2, like PPT1, possesses thioesterase activity and localizes to the lysosome. Since PPT2 could not substitute for PPT1 in correcting the metabolic defect in INCL cells and was unable to remove palmitate groups from palmitoylated proteins that are routinely used as substrates for PPT1it has been postulated that PPT2 possesses a different substrate specificity than PPT1.
-
分子量
- 34193
-
基因ID
- 5538
-
NCBI登录号
- NP_000301, NP_001136076
-
UniProt
- P50897
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-
