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ZMPSTE24 抗体 (C-Term)

This anti-ZMPSTE24 antibody is a 兔 多克隆 antibody detecting ZMPSTE24 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN389049
发货至: 中国

Quick Overview for ZMPSTE24 抗体 (C-Term) (ABIN389049)

抗原

See all ZMPSTE24 (Zmpste24) 抗体
ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

适用

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宿主

  • 37
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克隆类型

  • 38
多克隆

标记

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This ZMPSTE24 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4774
  • 抗原表位

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    AA 440-470, C-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-470 amino acids from the C-terminal region of human ZMPSTE24.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Afonso, Auclair, Boccara, Vantyghem, Katlama, Capeau, Vigouroux, Caron-Debarle: "LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: Role of ZMPSTE24 downregulation." in: Atherosclerosis, Vol. 245, pp. 200-11, (2016) (PubMed).

    Moulson, Go, Gardner, van der Wal, Smitt, van Hagen, Miner: "Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy." in: The Journal of investigative dermatology, Vol. 125, Issue 5, pp. 913-9, (2005) (PubMed).

  • 抗原

    ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

    别名

    ZMPSTE24

    背景

    ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

    分子量

    54813

    基因ID

    10269

    NCBI登录号

    NP_005848

    UniProt

    O75844
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