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ZMPSTE24 抗体 (AA 400-430)

Zmpste24 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04772 unconjugated
产品编号 ABIN389048
发货至: 中国
  • 抗原 See all ZMPSTE24 (Zmpste24) 抗体
    ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
    抗原表位
    • 11
    • 11
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-430
    适用
    • 44
    • 16
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 23
    • 8
    • 4
    • 4
    • 4
    • 2
    This ZMPSTE24 antibody is un-conjugated
    应用范围
    • 40
    • 34
    • 11
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the Central region of human ZMPSTE24.
    克隆位点
    RB04772
    亚型
    Ig Fraction
    Top Product
    Discover our top product Zmpste24 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Akinci, Sankella, Gilpin, Ozono, Garg, Agarwal: "Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide." in: Cold Spring Harbor molecular case studies, Vol. 3, Issue 1, pp. a001339, (2017) (PubMed).

    Liu, Wang, Chan, Tjia, Deng, Guan, Huang, Li, Chau, Chen, Pei, Pendas, Cadiñanos, López-Otín, Tse, Hutchison, Chen, Cao, Cheah, Tryggvason, Zhou: "Genomic instability in laminopathy-based premature aging." in: Nature medicine, Vol. 11, Issue 7, pp. 780-5, (2005) (PubMed).

    Corrigan, Kuszczak, Rusinol, Thewke, Hrycyna, Michaelis, Sinensky: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." in: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, (2005) (PubMed).

  • 抗原
    ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))
    别名
    ZMPSTE24 (Zmpste24 产品)
    别名
    DDBDRAFT_0189115 antibody, DDBDRAFT_0237846 antibody, DDB_0189115 antibody, DDB_0237846 antibody, F2N1.21 antibody, F2N1_21 antibody, STE24 antibody, FACE-1 antibody, FACE1 antibody, HGPS antibody, PRO1 antibody, Ste24p antibody, A530043O15Rik antibody, D030046F19 antibody, Face-1 antibody, MADB antibody, fi45a02 antibody, wu:fi45a02 antibody, zgc:55655 antibody, zinc metallopeptidase STE24 antibody, zinc metallopeptidase STE24 L homeolog antibody, CAAX prenyl protease antibody, Peptidase family M48 family protein antibody, zinc metallopeptidase, STE24 antibody, zinc metallopeptidase, STE24 homolog antibody, ZMPSTE24 antibody, zmpste24.L antibody, zmpste24 antibody, ATSTE24 antibody, Zmpste24 antibody
    背景
    ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
    分子量
    54813
    基因ID
    10269
    NCBI登录号
    NP_005848
    UniProt
    O75844
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