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CD73 抗体 (N-Term)

Cited in 4+ publications. This 兔 多克隆 anti-CD73 antibody (Clone RB02844) specifically detects CD73 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN388749
发货至: 中国
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Quick Overview for CD73 抗体 (N-Term) (ABIN388749)

抗原

See all CD73 (NT5E) 抗体
CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

适用

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克隆类型

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多克隆

标记

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This CD73 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB02844
  • 抗原表位

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    AA 1-30, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This CD73 (NT5E) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CD73 (NT5E).

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Kim, Piao, Pak, Chung, Han, Hong, Jun, Shim, Choi, Kim: "Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction." in: Stem cells and development, Vol. 24, Issue 5, pp. 575-86, (2015) (PubMed).

    Doherty, Bai, Hanidziar, Longhi, Lawlor, Putheti, Csizmadia, Nowak, Cheifetz, Moss, Robson: "CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease." in: European journal of immunology, Vol. 42, Issue 11, pp. 3062-72, (2012) (PubMed).

    Andrade, Lopez, Noronha, Wink, Borojevic, Margis, Lenz, Battastini, Guma: "Ecto-5'-nucleotidase/CD73 knockdown increases cell migration and mRNA level of collagen I in a hepatic stellate cell line." in: Cell and tissue research, Vol. 344, Issue 2, pp. 279-86, (2011) (PubMed).

    Nadri, Soleimani, Mobarra, Amini: "Expression of dopamine-associated genes on conjunctiva stromal-derived human mesenchymal stem cells." in: Biochemical and biophysical research communications, Vol. 377, Issue 2, pp. 423-8, (2008) (PubMed).

  • 抗原

    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

    别名

    CD73 (NT5E)

    背景

    Ecto-5-prime-nucleotidase catalyzes conversion at neutral pH of purine 5-prime mononucleotides to nucleosides. The enzyme consists of a dimer of 2 identical 70 kD subunits tethered by a glycosyl phosphatidyl inositol moeity to the exterior plasma membrane surface. The enzyme, a marker of lymphocyte differentiation is associated in deficiency with a variety of immunodeficiency diseases. The preferred substrate is AMP. The NT5 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations.

    分子量

    63368

    基因ID

    4907

    NCBI登录号

    NP_001191742, NP_002517

    UniProt

    P21589

    途径

    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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