CD73 抗体 (N-Term)
Quick Overview for CD73 抗体 (N-Term) (ABIN388749)
抗原
See all CD73 (NT5E) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This CD73 (NT5E) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CD73 (NT5E).
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亚型
- Ig Fraction
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应用备注
- IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction." in: Stem cells and development, Vol. 24, Issue 5, pp. 575-86, (2015) (PubMed).
: "CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease." in: European journal of immunology, Vol. 42, Issue 11, pp. 3062-72, (2012) (PubMed).
: "Ecto-5'-nucleotidase/CD73 knockdown increases cell migration and mRNA level of collagen I in a hepatic stellate cell line." in: Cell and tissue research, Vol. 344, Issue 2, pp. 279-86, (2011) (PubMed).
: "Expression of dopamine-associated genes on conjunctiva stromal-derived human mesenchymal stem cells." in: Biochemical and biophysical research communications, Vol. 377, Issue 2, pp. 423-8, (2008) (PubMed).
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Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction." in: Stem cells and development, Vol. 24, Issue 5, pp. 575-86, (2015) (PubMed).
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- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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别名
- CD73 (NT5E)
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背景
- Ecto-5-prime-nucleotidase catalyzes conversion at neutral pH of purine 5-prime mononucleotides to nucleosides. The enzyme consists of a dimer of 2 identical 70 kD subunits tethered by a glycosyl phosphatidyl inositol moeity to the exterior plasma membrane surface. The enzyme, a marker of lymphocyte differentiation is associated in deficiency with a variety of immunodeficiency diseases. The preferred substrate is AMP. The NT5 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations.
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分子量
- 63368
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基因ID
- 4907
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NCBI登录号
- NP_001191742, NP_002517
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UniProt
- P21589
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途径
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
抗原
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