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ATG4B 抗体 (AA 258-284)

This anti-ATG4B antibody is a 兔 多克隆 antibody detecting ATG4B in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN388497
发货至: 中国

Quick Overview for ATG4B 抗体 (AA 258-284) (ABIN388497)

抗原

See all ATG4B 抗体
ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

适用

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宿主

  • 104
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克隆类型

  • 101
  • 8
多克隆

标记

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This ATG4B antibody is un-conjugated

应用范围

  • 83
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB11843
  • 抗原表位

    • 20
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    • 1
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    • 1
    AA 258-284

    预测反应

    B, C, Zf, M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-284 amino acids from human ATG4B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

    别名

    ATG4B

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4, a cysteine protease required for autophagy, cleaves the C-terminal part of MAP1LC3 to form the activated molecule LC3-I. LC3-I is subsequently conjugated with phosphatidylethanolamine at the C-terminal glycine to form LC3-II, a marker for autophagy via its capacity to bind to autophagosomes.

    分子量

    44294

    基因ID

    23192

    NCBI登录号

    NP_037457, NP_847896

    UniProt

    Q9Y4P1

    途径

    Autophagy
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