SIGLEC7 抗体 (C-Term)
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Quick Overview for SIGLEC7 抗体 (C-Term) (ABIN388430)
抗原
See all SIGLEC7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 407-438, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SIGLEC7 (D-siglec) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-438 amino acids from the C-terminal region of human SIGLEC7 (D-siglec).
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亚型
- Ig Fraction
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anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 377-467) antibody
SIGLEC7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 38-121) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibody (PE)SIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 PE
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-467) antibodySIGLEC7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) antibodySIGLEC7 适用: 人 FACS 宿主: 小鼠 Monoclonal 6-434 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 18-353) antibodySIGLEC7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 1-30), (N-Term) antibodySIGLEC7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2711 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (AA 407-438) antibodySIGLEC7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
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别名
- SIGLEC7 (D-siglec)
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背景
- SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal Ig-like domain. Both variants contain 2 C2-set N-terminal Ig-like domains, a transmembrane domain, and a cytoplasmic tail with a putative ITIM and a putative SLAM-like tyrosine-based motif. The conserved arginine residue thought to be essential for sialic acid binding in other SIGLECs is replaced by a glutamine in SLGS and by a cysteine in SLGL. RT-PCR analysis detected high expression of both variants in spleen and small intestine, and SLGS was highly expressed in adrenal gland and SLGL was highly expressed in bone marrow.
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分子量
- 51143
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基因ID
- 27036
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NCBI登录号
- NP_001264130, NP_055200, NP_057627
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UniProt
- Q9Y286
抗原
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