BNIP3 抗体 (AA 215-252)
Quick Overview for BNIP3 抗体 (AA 215-252) (ABIN388117)
抗原
See all BNIP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 215-252
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-252 amino acids from human BNIP3.
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亚型
- Ig Fraction
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应用备注
- IF: 1:500. IF: 1:50~100. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
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有效期
- 6 months
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Autophagy and Bcl-2/BNIP3 death regulatory pathway in non-small cell lung carcinomas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 121, Issue 7, pp. 592-604, (2013) (PubMed).
: "Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments." in: Cancer research, Vol. 72, Issue 16, pp. 3938-47, (2012) (PubMed).
: "Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 296, Issue 3, pp. G499-509, (2009) (PubMed).
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Autophagy and Bcl-2/BNIP3 death regulatory pathway in non-small cell lung carcinomas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 121, Issue 7, pp. 592-604, (2013) (PubMed).
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- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
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别名
- BNIP3 (NIP3)
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背景
- NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
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分子量
- 27832
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基因ID
- 664
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NCBI登录号
- NP_004043
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UniProt
- Q12983
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途径
- Autophagy, Brown Fat Cell Differentiation
抗原
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