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SENP1 抗体 (C-Term)

This anti-SENP1 antibody is a 兔 多克隆 antibody detecting SENP1 in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN388043
发货至: 中国

Quick Overview for SENP1 抗体 (C-Term) (ABIN388043)

抗原

See all SENP1 抗体
SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

适用

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宿主

  • 67
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克隆类型

  • 57
  • 13
多克隆

标记

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This SENP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB00649-RB0650
  • 抗原表位

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    AA 560-590, C-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-590 amino acids from the C-terminal region of human SENP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Rohira, Chen, Allen, Johnson: "Covalent small ubiquitin-like modifier (SUMO) modification of Maf1 protein controls RNA polymerase III-dependent transcription repression." in: The Journal of biological chemistry, Vol. 288, Issue 26, pp. 19288-95, (2013) (PubMed).

    Meinecke, Cinski, Baier, Peters, Dankbar, Wille, Drynda, Mendoza, Gay, Hay, Ink, Gay, Pap: "Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5073-8, (2007) (PubMed).

  • 抗原

    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

    别名

    SENP1

    背景

    SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.

    分子量

    73481

    基因ID

    29843

    NCBI登录号

    NP_001254523, NP_001254524

    UniProt

    Q9P0U3

    途径

    Positive Regulation of Endopeptidase Activity
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