SENP1 抗体 (N-Term)
Quick Overview for SENP1 抗体 (N-Term) (ABIN388042)
抗原
See all SENP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 28-59, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SENP1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
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别名
- SENP1
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背景
- SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.
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分子量
- 73481
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基因ID
- 29843
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NCBI登录号
- NP_001254523, NP_001254524
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UniProt
- Q9P0U3
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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