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SENP1 抗体 (N-Term)

Cited in 2+ publications. This 兔 多克隆 anti-SENP1 antibody (Clone RB0647) specifically detects SENP1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN388042
发货至: 中国
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Quick Overview for SENP1 抗体 (N-Term) (ABIN388042)

抗原

See all SENP1 抗体
SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

适用

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宿主

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克隆类型

  • 59
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多克隆

标记

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This SENP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB0647
  • 抗原表位

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    AA 28-59, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SENP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Kim, Choi, Kim, Kim, Lee, Kim, Lee, Choi, Kim, Kim, Chung, Baek: "Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis." in: Nature cell biology, Vol. 8, Issue 6, pp. 631-9, (2006) (PubMed).

    Chen, Chen: "MDM2-ARF complex regulates p53 sumoylation." in: Oncogene, Vol. 22, Issue 34, pp. 5348-57, (2003) (PubMed).

  • 抗原

    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

    别名

    SENP1

    背景

    SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.

    分子量

    73481

    基因ID

    29843

    NCBI登录号

    NP_001254523, NP_001254524

    UniProt

    Q9P0U3

    途径

    Positive Regulation of Endopeptidase Activity
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