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SUMO1 抗体 (C-Term)

This anti-SUMO1 antibody is a 兔 多克隆 antibody detecting SUMO1 in WB, FACS 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN388027
发货至: 中国

Quick Overview for SUMO1 抗体 (C-Term) (ABIN388027)

抗原

See all SUMO1 抗体
SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SUMO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB0632
  • 抗原表位

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    AA 55-86, C-Term

    预测反应

    B, M, Pig, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SUMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-86 amino acids from the C-terminal region of human SUMO1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Laoong-u-thai, Zhao, Phongdara, Ako, Yang: "Identifications of SUMO-1 cDNA and its expression patterns in Pacific white shrimp Litopeanaeus vannamei." in: International journal of biological sciences, Vol. 5, Issue 2, pp. 205-14, (2009) (PubMed).

    Rathke, Baarends, Jayaramaiah-Raja, Bartkuhn, Renkawitz, Renkawitz-Pohl: "Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila." in: Journal of cell science, Vol. 120, Issue Pt 9, pp. 1689-700, (2007) (PubMed).

    Degerny, Monte, Beaudoin, Jaffray, Portois, Hay, de Launoit, Baert: "SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24330-8, (2005) (PubMed).

  • 抗原

    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

    别名

    SUMO1

    背景

    Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.

    分子量

    11557

    基因ID

    7341

    NCBI登录号

    NP_001005781, NP_001005782, NP_003343

    UniProt

    P63165

    途径

    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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