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SUMO1 抗体

There are 3+ publications for this product available. The 小鼠 单克隆 anti-SUMO1 antibody is suitable to detect SUMO1 in samples from 人. It has been validated for WB, IF, FACS 和 IHC (p).
产品编号 ABIN387785
发货至: 中国
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Quick Overview for SUMO1 抗体 (ABIN387785)

抗原

See all SUMO1 抗体
SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SUMO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

66AT1273-94
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    Purified recombinant GST-SUMO1 fusion protein was used as immunogen.

    亚型

    IgG1
  • 应用备注

    IF: 1:25. WB: 1:100~500. WB: 1:4000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25. IHC: 1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Namanja, Li, Su, Wong, Lu, Colson, Wu, Li, Chen: "Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis." in: The Journal of biological chemistry, Vol. 287, Issue 5, pp. 3231-40, (2012) (PubMed).

    Truong, Lee, Chen: "Small ubiquitin-like modifier (SUMO) modification of E1 Cys domain inhibits E1 Cys domain enzymatic activity." in: The Journal of biological chemistry, Vol. 287, Issue 19, pp. 15154-63, (2012) (PubMed).

    Li, Perkins, Su, Ma, Colson, Horne, Chen: "Gold nanoparticles as a platform for creating a multivalent poly-SUMO chain inhibitor that also augments ionizing radiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 11, pp. 4092-7, (2012) (PubMed).

  • 抗原

    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

    别名

    SUMO1

    背景

    This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.

    分子量

    11557

    基因ID

    7341

    NCBI登录号

    NP_001005781, NP_001005782, NP_003343

    UniProt

    P63165

    途径

    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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