Angiotensin I Converting Enzyme 1 抗体
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Quick Overview for Angiotensin I Converting Enzyme 1 抗体 (ABIN379980)
抗原
See all Angiotensin I Converting Enzyme 1 (ACE) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antigen is CD143, the epitope is apparently localized in the N-terminal portion of the protein. Antigen distribution: Tissue sections: Topographically the degree of expression correlates with the proportion of smooth muscle cells and elastic fibres of the vessel wall. ACE is predominantely expressed by small muscular arteries and by arterioles, whereas small and large veins do not usually express ACE. However, no ACE could be detected in the endothelial cells of kidney. Constitutively ACE is expressed on endothelial cells in different diseases like hypertension, myocardial infarction, sarcoidosis, diabetes. Specificity: Human: denatured ACE. Other species: not tested.
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纯化方法
- Affinity purified
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免疫原
- purified ACE from human lung and kidney
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应用备注
- Approved: IHC, IHC-P (1:50)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.5 mL distilled water
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS pH 7.2, 10 mg/mL BSA, 0.1 % Kathon
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储存液
- Kathon CG
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储存条件
- 4 °C
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储存方法
- Store at 4°C.
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- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
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别名
- ACE / DCP1 / CD143
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背景
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Name/Gene ID: ACE
Subfamily: Metallopeptidase M2
Family: Protease
Synonyms: ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA -
基因ID
- 1636
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UniProt
- P12821
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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