S100A8 抗体
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北京 101111
Quick Overview for S100A8 抗体 (ABIN379950)
抗原
See all S100A8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antigen is MRP8, the epitope is suspected in the N- or C- terminal domain. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes. It is absent from other blood cells. In cultured monocytes, maximum MRP8 levels occur after 3 - 4 days. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages increasingly synthesise MRP8 during the late stages of inflammation. A low MRP8 (and high MRP14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis, MRP8 and MRP14 positive cells consist of different subpopulations. During early inflammation endothelial cells are also positive with MRP8 / MRP14. Specificity: Human: granulocytes, stimulated monocytes and macrophages. Other: rat, cow, pig (TNF-alpha/IL-1 alpha induced inflammation of the skin).
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纯化方法
- Affinity purified
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免疫原
- Cultured human monocytes
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.5 mL distilled water
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4°C.
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- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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别名
- S100A8 / MRP8
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背景
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Name/Gene ID: S100A8
Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8 -
基因ID
- 6279
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UniProt
- P05109
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途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
抗原
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