S100A8 抗体 (Biotin)
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- 抗原 See all S100A8 抗体
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This S100A8 antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- The antigen is MRP8, the epitope is suspected in the central portion of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes but not in other blood cells. In cultured monocytes, maximum MRP8 expression is found after 3 - 4 days. Myeloid leukaemia stains positively. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP8 increasingly during the late stages of inflammation. A low MRP8 (and high MRP- 14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis or chronic rejection after allograft transplantation, MRP8 and MRP14 positive cells consist of different subpopulations. Specificity: Human: MRP8 in stimulated monocytes and macrophages in late phase or chronic inflammation. Other: The antibody reacts with bovine spleen but does not react with rat tissues. It shows a diffuse reaction with swine spleen.
- 纯化方法
- Affinity purified
- 免疫原
- Cultured human monocytes
- 克隆位点
- 8-5C2
- Top Product
- Discover our top product S100A8 Primary Antibody
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- 应用备注
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Approved: ELISA, IHC, IHC-P
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.5 mL distilled water
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from PBS pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C.
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- 抗原
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- 别名
- S100A8 / MRP8 (S100A8 产品)
- 别名
- 60B8AG antibody, CAGA antibody, CFAG antibody, CGLA antibody, CP-10 antibody, L1Ag antibody, MA387 antibody, MIF antibody, MRP8 antibody, NIF antibody, P8 antibody, Mrp8 antibody, S100A8 antibody, 60B8Ag antibody, AI323541 antibody, B8Ag antibody, CFAg antibody, Caga antibody, p8 antibody, MRP-8 antibody, S100 calcium binding protein A8 antibody, S100 calcium binding protein A8 (calgranulin A) antibody, S100A8 antibody, S100a8 antibody
- 背景
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Name/Gene ID: S100A8
Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8 - 基因ID
- 6279
- UniProt
- P05109
- 途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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