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S100A8 抗体

This anti-S100A8 antibody is a 小鼠 单克隆 antibody detecting S100A8 in IHC, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN379948
发货至: 中国

Quick Overview for S100A8 抗体 (ABIN379948)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This S100A8 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

8-5C2
  • 特异性

    The antigen is MRP8, the epitope is suspected in the central portion of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes but not in other blood cells. In cultured monocytes, maximum MRP8 is expressed after 3 - 4 days. Myeloid leukaemia stain positive. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP8 increasingly during the late stages of inflammation. A low MRP8 (and high MRP- 14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis or chronic rejection after allograft transplantation, MRP8 and MRP14 positive cells consist of different subpopulations. Specificity: Human: MRP8 in stimulated monocytes and macrophages in late phase or chronic inflammation. Other: The antibody reacts with bovine spleen but does not react with rat tissues. It shows a diffuse reaction with swine spleen.

    纯化方法

    Affinity purified

    免疫原

    Cultured human monocytes
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.5 mL distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS  pH 7.2, 5 mg/mL BSA, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 4°C.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    S100A8 / MRP8

    背景

    Name/Gene ID: S100A8

    Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8

    基因ID

    6279

    UniProt

    P05109

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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