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S100A8 抗体

S100A8 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 8-5C2 unconjugated
产品编号 ABIN379948
发货至: 中国
  • 抗原 See all S100A8 抗体
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This S100A8 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antigen is MRP8, the epitope is suspected in the central portion of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes but not in other blood cells. In cultured monocytes, maximum MRP8 is expressed after 3 - 4 days. Myeloid leukaemia stain positive. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP8 increasingly during the late stages of inflammation. A low MRP8 (and high MRP- 14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis or chronic rejection after allograft transplantation, MRP8 and MRP14 positive cells consist of different subpopulations. Specificity: Human: MRP8 in stimulated monocytes and macrophages in late phase or chronic inflammation. Other: The antibody reacts with bovine spleen but does not react with rat tissues. It shows a diffuse reaction with swine spleen.
    纯化方法
    Affinity purified
    免疫原
    Cultured human monocytes
    克隆位点
    8-5C2
    Top Product
    Discover our top product S100A8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    0.5 mL distilled water
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS  pH 7.2, 5 mg/mL BSA, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 4°C.
  • 抗原
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    别名
    S100A8 / MRP8 (S100A8 产品)
    背景
    Name/Gene ID: S100A8

    Synonyms: S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8
    基因ID
    6279
    UniProt
    P05109
    途径
    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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