CD44 抗体 (Biotin)
Quick Overview for CD44 抗体 (Biotin) (ABIN376015)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human/Ma's Night Monkey CD44, Mr 80 - 95 kDa
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产品特性
- Mouse Anti-Human CD44-BIOT
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纯化方法
- Purified
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免疫原
- Purified T cells from human lymph nodes
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亚型
- IgG2a
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应用备注
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Working Dilution:
10 µL/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. -
限制
- 仅限研究用
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注意事项
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
储存条件
- 4 °C
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: "Genetic modification of primary human B cells to model high-grade lymphoma." in: Nature communications, Vol. 10, Issue 1, pp. 4543, (2020) (PubMed).
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: "Genetic modification of primary human B cells to model high-grade lymphoma." in: Nature communications, Vol. 10, Issue 1, pp. 4543, (2020) (PubMed).
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- CD44
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别名
- CD44
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背景
- CD44, also known as phagocytic glycoprotein-1 (Pgp-1) and the receptor for hyaluronate, exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation.
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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