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CD44 抗体 (Biotin)

This anti-CD44 antibody is a 小鼠 单克隆 antibody detecting CD44 in FACS, IHC, IHC (p) 和 IP. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN376015
发货至: 中国

Quick Overview for CD44 抗体 (Biotin) (ABIN376015)

抗原

See all CD44 抗体
CD44

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

克隆位点

F10-44-2
  • 特异性

    Human/Ma's Night Monkey CD44, Mr 80 - 95 kDa

    产品特性

    Mouse Anti-Human CD44-BIOT

    纯化方法

    Purified

    免疫原

    Purified T cells from human lymph nodes

    亚型

    IgG2a
  • 应用备注

    Working Dilution:
    10 µL/10^6 cells
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

    限制

    仅限研究用
  • 注意事项

    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C
  • Caeser, Di Re, Krupka, Gao, Lara-Chica, Dias, Cooke, Fenner, Usheva, Runge, Beer, Eldaly, Pak, Park, Vassiliou, Huntly, Mupo, Bashford-Rogers, Hodson: "Genetic modification of primary human B cells to model high-grade lymphoma." in: Nature communications, Vol. 10, Issue 1, pp. 4543, (2020) (PubMed).

  • 抗原

    CD44

    别名

    CD44

    背景

    CD44, also known as phagocytic glycoprotein-1 (Pgp-1) and the receptor for hyaluronate, exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation.

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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