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CD25 抗体 (PE-Cy7)

This anti-CD25 antibody is a 大鼠 单克隆 antibody detecting CD25 in FACS. Suitable for 小鼠.
产品编号 ABIN375558
发货至: 中国

Quick Overview for CD25 抗体 (PE-Cy7) (ABIN375558)

抗原

See all CD25 (IL2RA) 抗体
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD25 antibody is conjugated to PE-Cy7

应用范围

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Flow Cytometry (FACS)

克隆位点

7D4
  • 特异性

    Mouse CD25, Mr 55 kDa

    产品特性

    Rat Anti-Mouse CD25-PE/CY7

    纯化方法

    Purified

    免疫原

    IL-2 dependent BALB/c helper T cell clone, HT2

    亚型

    IgM
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Neut - Reported in literature , Block - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, SPRD, and PE/CY7 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    别名

    CD25

    背景

    The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220 low TdT - sIg - pre-B II and CD45R/B220 low TdT - sIgM + sIgD - immature B cells, but not on the CD45R/B220 low TdT + sIg - pro-B/pre-B I stage nor on CD45R/B220 high TdT - sIgM + sIgD + mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus.

    途径

    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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