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- 抗原 See all LAMP2 抗体
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LAMP2 antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 特异性
- Human/Rhesus/African Green Monkey CD107b, Mr 100-120 kDa
- 产品特性
- Mouse Anti-Human CD107b-BIOT
- 纯化方法
- Purified
- 免疫原
- Human adherent peripheral blood cells
- 克隆位点
- H4B4
- 亚型
- IgG1
- Top Product
- Discover our top product LAMP2 Primary Antibody
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anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 191-362) antibody
LAMP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-168) antibodyLAMP2 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 6A10H10 unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-168) antibodyLAMP2 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 8E2F2 unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 301-411) antibodyLAMP2 适用: 人, 小鼠, 大鼠, Pig WB, FACS, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 193-375) antibodyLAMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibodyLAMP2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibodyLAMP2 适用: 人 WB, FACS, ICC, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal H4B4 unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibodyKO Validated LAMP2 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 54-268) antibodyLAMP2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 30-127) antibodyLAMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G10 unconjugated
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- 应用备注
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Working Dilution:
10 µL/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. - 限制
- 仅限研究用
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- 注意事项
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - 储存条件
- 4 °C
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- 抗原
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- 别名
- CD107b (LAMP2 产品)
- 背景
- CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium.
- 途径
- Autophagy
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