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CD25 抗体 (APC)

IL2RA 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 3C7 APC
产品编号 ABIN375406
发货至: 中国
  • 抗原 See all CD25 (IL2RA) 抗体
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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    小鼠
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    大鼠
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    单克隆
    标记
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    This CD25 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD25, Mr 55 kDa
    产品特性
    Rat Anti-Mouse CD25-APC
    纯化方法
    Purified
    免疫原
    IL-2 dependent BALB/c helper T cell clone HT2
    克隆位点
    3C7
    亚型
    IgG2b
    Top Product
    Discover our top product IL2RA Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Neut - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE, APC, SPRD, PE/CY7, and AF700 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    Inhibition of IL-2 or mitogen-induced T cell proliferation, In vitro blocking of IL-2 binding

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    别名
    CD25 (IL2RA 产品)
    别名
    CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
    背景
    The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity α chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. Expression of CD25 on activated T lymphocytes is transitory and endogenously regulated. CD25 is expressed on precursor B cells in bone marrow. Its expression is initiated by functional rearrangement and expression of IgM heavy chain genes and is down-regulated when immature B cells mature and express IgD. It is expressed at a higher level on CD4 + CD8 + thymocytes. It is also expressed on cultured epidermal Langerhans cells. The biochemical features of murine CD25 have been characterized in detail.
    途径
    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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