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MARK2 抗体 (Internal Region)

The 山羊 多克隆 anti-MARK2 antibody (ABIN375213) specifically detects MARK2 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN375213
发货至: 中国
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Quick Overview for MARK2 抗体 (Internal Region) (ABIN375213)

抗原

See all MARK2 抗体
MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

适用

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宿主

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山羊

克隆类型

  • 64
  • 21
多克隆

标记

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This MARK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Internal Region

    特异性

    This antibdoy reacts to MARK2.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Bovine.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-QNGKDSTAPQR, from the internal region of the protein sequence
  • 应用备注

    ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0,5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

    别名

    MARK2

    背景

    MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein. Role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells.Synonyms: 2, ELKL motif kinase, EMK1, MAP/microtubule affinity-regulating kinase, MARK2, PAR1 homolog, Serine/threonine-protein kinase

    基因ID

    2011

    NCBI登录号

    NP_001034558

    UniProt

    Q7KZI7

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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