电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

FGF23 抗体 (Internal Region)

FGF23 适用: 人 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN375198
发货至: 中国
  • 抗原 See all FGF23 抗体
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    抗原表位
    • 15
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 58
    • 19
    • 14
    宿主
    • 53
    • 23
    • 2
    山羊
    克隆类型
    • 57
    • 21
    多克隆
    标记
    • 41
    • 11
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF23 antibody is un-conjugated
    应用范围
    • 42
    • 33
    • 17
    • 11
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-RHTRSAEDDS ERD
    特异性
    This antibody recognizes FGF23.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography
    免疫原
    Synthetic peptide from the internal region of Human FGF23 (NP_065689.1) Genename: FGF23
    Top Product
    Discover our top product FGF23 Primary Antibody
  • 应用备注
    ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    别名
    FGF23 (FGF23 产品)
    别名
    FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody
    背景
    Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) [MIM:193100]. ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC) [MIM:211900]. HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.Synonyms: FGF-23, Fibroblast growth factor 23, HYPF, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor
    分子量
    27.9 kDa (NP_065689.1).
    基因ID
    8074
    NCBI登录号
    NP_065689
    UniProt
    Q9GZV9
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
You are here:
客服