FGF23 抗体 (Internal Region)
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Quick Overview for FGF23 抗体 (Internal Region) (ABIN375198)
抗原
See all FGF23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-RHTRSAEDDS ERD
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特异性
- This antibody recognizes FGF23.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography
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免疫原
- Synthetic peptide from the internal region of Human FGF23 (NP_065689.1) Genename: FGF23
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anti-Fibroblast Growth Factor 23 (FGF23) (AA 25-251) antibody
FGF23 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (AA 21-120) antibodyFGF23 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (AA 25-251) antibodyFGF23 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) antibodyFGF23 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal FG322-3 unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (AA 79-160) antibodyFGF23 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (AA 1-251) antibodyFGF23 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (Internal Region) antibodyVerified FGF23 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (AA 25-251) antibodyFGF23 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) antibodyFGF23 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1-2# unconjugated
anti-Fibroblast Growth Factor 23 (FGF23) (Internal Region) antibodyVerified FGF23 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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别名
- FGF23
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背景
- Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) [MIM:193100]. ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC) [MIM:211900]. HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.Synonyms: FGF-23, Fibroblast growth factor 23, HYPF, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor
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分子量
- 27.9 kDa (NP_065689.1).
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基因ID
- 8074
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NCBI登录号
- NP_065689
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UniProt
- Q9GZV9
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
抗原
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