FZD7 抗体 (C-Term)
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Quick Overview for FZD7 抗体 (C-Term) (ABIN374921)
抗原
See all FZD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-RFYHRLSHSS KGET
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特异性
- This antibody recognizes Frizzled 7 (C-term).
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-RFYHRLSHSSKGET from the C Terminus of Human FZD7 (NP_003498.1).
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anti-Frizzled Family Receptor 7 (FZD7) (AA 501-574) antibody
FZD7 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (AA 155-253) antibodyFZD7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibodyFZD7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (N-Term) antibodyFZD7 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibodyVerified FZD7 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibodyFZD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (AA 161-239) antibodyFZD7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (N-Term) antibodyFZD7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (N-Term) antibodyFZD7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Bat, 猴, Pig, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 7 (FZD7) (C-Term) antibodyFZD7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Detection Limit Dilution: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 60 kDa band observed in lysates of cell lines HEK293 andHepG2 (calculated MW of 63.0 kDa according to NP_003498.1). Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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别名
- FZD7 / Frizzled-7
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背景
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Frizzled family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. Frizzled 7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Frizzled 7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries.Synonyms: Fz-7, mFz7
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基因ID
- 8324
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NCBI登录号
- NP_003498
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UniProt
- O75084
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途径
- WNT signaling, Stem Cell Maintenance
抗原
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