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OGG1 抗体 (Internal Region)

The 山羊 多克隆 anti-OGG1 antibody is suitable to detect OGG1 in samples from 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN374768
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for OGG1 抗体 (Internal Region) (ABIN374768)

抗原

See all OGG1 抗体
OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

适用

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小鼠, 大鼠

宿主

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山羊

克隆类型

  • 52
  • 21
多克隆

标记

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This OGG1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 16
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    Internal Region

    特异性

    This antibody reacts to OGG1.

    交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Rat.

    纯化方法

    Affinity chromatography

    免疫原

    Peptide with sequence C-HPKTSQAKGPSPLANK, from the internal region of the protein sequence
  • 应用备注

    Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

    别名

    OGG1

    背景

    The Ogg1 gene encodes a DNA repair enzyme (N glycosylase/DNA lyase) that incises DNA at 8 oxoG residues. N glycosylase/DNA lyase excises 7,8 dihydro 8 oxoguanine and 2,6 diamino 4 hydroxy 5 N methylformamidopyrimidine (FAPY) from damaged DNA. N glycosylase/DNA lyase has a beta lyase activity that nicks DNA 3' to the lesion. Alternative splicing of the C terminal region of the Ogg1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N terminal region in common. Many alternative splice variants for this gene have been described, but the full length nature for every variant has not been determined. The N terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.Synonyms: MMH, MUTM, N-glycosylase/DNA lyase, OGH1

    基因ID

    4968, 9606

    UniProt

    O15527

    途径

    DNA Damage Repair
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