Fibulin 5 抗体 (C-Term, Internal Region)
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Quick Overview for Fibulin 5 抗体 (C-Term, Internal Region) (ABIN374733)
抗原
See all Fibulin 5 (FBLN5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term, Internal Region
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特异性
- This antibody reacts to FBLN5.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-RPIKGPREIQLDLE, from the internal region (near the C Terminus) of the protein sequence
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应用备注
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Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Fibulin 5 (FBLN5)
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别名
- Fibulin-5
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背景
- Fibulin 5(FBLN5), the active form of which is about 66 kDa (unprocessed precursor 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin 5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin 5 is also a good marker of skin ageing and that the earlier loss of fibulin 5 may involve age-dependent changes in other elastic fibre components.Synonyms: DANCE, Developmental arteries and neural crest EGF-like protein, FBLN5, FIBL-5, UP50, Urine p50 protein
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基因ID
- 10516
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NCBI登录号
- NP_006320
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UniProt
- Q9UBX5
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途径
- SARS-CoV-2 Protein Interactome
抗原
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