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ALOX5 抗体 (C-Term)

ALOX5 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374732
发货至: 中国
  • 抗原 See all ALOX5 抗体
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    抗原表位
    • 16
    • 15
    • 15
    • 12
    • 9
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 90
    • 79
    • 60
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬
    宿主
    • 104
    • 9
    • 1
    山羊
    克隆类型
    • 103
    • 11
    多克隆
    标记
    • 48
    • 11
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    This ALOX5 antibody is un-conjugated
    应用范围
    • 62
    • 39
    • 39
    • 26
    • 25
    • 15
    • 9
    • 7
    • 7
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to Arachidonate 5-lipoxygenase.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Canine.
    Species reactivity (tested):Human, Rat.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-ERNKKKQLPYYYLSPD, from the C Terminus of the protein sequence Genename: ALOX5
    Top Product
    Discover our top product ALOX5 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    别名
    ALOX5 / LOG5 (ALOX5 产品)
    别名
    5-LO antibody, 5-LOX antibody, 5LPG antibody, LOG5 antibody, 5LO antibody, 5LX antibody, AI850497 antibody, F730011J02 antibody, LOX5A antibody, si:dkey-194n13.2 antibody, lox5 antibody, arachidonate 5-lipoxygenase antibody, arachidonate 5-lipoxygenase a antibody, Arachidonate 5-lipoxygenase antibody, ALOX5 antibody, Alox5 antibody, alox5a antibody, AFUA_4G02770 antibody, AOR_1_1362014 antibody, lox5 antibody
    背景
    The enzyme 5 Lipoxygenase (5 LO) plays a key role in regulating the production of leukotrienes (LTs). Overproduction of LTs contributes to several diseases, most notably chronic inflammatory diseases, including asthma, fibrosis and atherosclerosis. Recent work has demonstrated that the activity of 5 LO is regulated by PKA phosphorylation of serine 523 in 5 LO. Under normal conditions, this phosphorylation may be important in limiting inflammation. Abnormal signaling through cAMP and PKA, then, could contribute to a variety of diseases, including those characterized by chronic inflammation.Synonyms: 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase
    基因ID
    240, 9606
    UniProt
    P09917
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