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Stathmin 1 抗体 (C-Term)

There are 2+ publications for this product available. The 山羊 多克隆 anti-Stathmin 1 antibody is suitable to detect Stathmin 1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN374648
发货至: 中国
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Quick Overview for Stathmin 1 抗体 (C-Term) (ABIN374648)

抗原

See all Stathmin 1 (STMN1) 抗体
Stathmin 1 (STMN1)

适用

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人, 小鼠, 大鼠

宿主

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山羊

克隆类型

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多克隆

标记

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This Stathmin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody is expected to cross-react with isoform 1a (NP_005554.1, NP_981944.1, NP_981946.1) only. The three reported isoforms (NP_005554.1, NP_981944.1 and NP_981946.1) represent identical protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide (C-KNKESKDPADETEAD) from C-terminus of Human STMN1 (NP_005554.1, NP_981944.1, NP_981946.1)
  • 应用备注

    ELISA: 1/1000. Western Blot: 1-3 μg/mL. Immunohistochemistry on Paraffin Sections: 3.75 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Watabe-Rudolph, Song, Lausser, Schnack, Begus-Nahrmann, Scheithauer, Rettinger, Otto, Tumani, Thal, Attems, Jellinger, Kestler, von Arnim, Rudolph: "Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease." in: Neurology, Vol. 78, Issue 8, pp. 569-77, (2012) (PubMed).

    Wallukat, Muñoz Saravia, Haberland, Bartel, Araujo, Valda, Duchen, Diaz Ramirez, Borges, Schimke: "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients." in: Journal of the American College of Cardiology, Vol. 55, Issue 5, pp. 463-8, (2010) (PubMed).

  • 抗原

    Stathmin 1 (STMN1)

    别名

    Stathmin / STMN1

    背景

    STMN1 is a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

    分子量

    17.3kDa (NP_005554.1, NP_981944.1 and NP_981946.1).

    基因ID

    3925, 9606

    UniProt

    P16949

    途径

    MAPK Pathway, Microtubule Dynamics
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