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PAI1 抗体 (Internal Region)

SERPINE1 适用: 人, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374547
发货至: 中国
  • 抗原 See all PAI1 (SERPINE1) 抗体
    PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
    抗原表位
    • 15
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    • 7
    • 7
    • 7
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    • 6
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    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 137
    • 36
    • 18
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 犬
    宿主
    • 109
    • 28
    • 8
    • 5
    • 1
    山羊
    克隆类型
    • 122
    • 30
    多克隆
    标记
    • 84
    • 17
    • 15
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PAI1 antibody is un-conjugated
    应用范围
    • 111
    • 66
    • 48
    • 26
    • 26
    • 18
    • 16
    • 16
    • 13
    • 11
    • 9
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    • 6
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    • 2
    • 2
    • 1
    • 1
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-GFKIDDKGMA PALRH
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog).
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Synthetic peptide (C-GFKIDDKGMAPALRH) from the internal region of SERPINE1 (NP_000593.1, NP_001158885.1). Genename: SERPINE1
    Top Product
    Discover our top product SERPINE1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Cipollone, Felicioni, Sarzani, Ucchino, Spigonardo, Mandolini, Malatesta, Bucci, Mammarella, Santovito, de Lutiis, Marchetti, Mezzetti, Buttitta: "A unique microRNA signature associated with plaque instability in humans." in: Stroke, Vol. 42, Issue 9, pp. 2556-63, (2011) (PubMed).

  • 抗原
    PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
    别名
    SERPINE1 / PAI1 (SERPINE1 产品)
    别名
    PAI antibody, PAI-1 antibody, PAI1 antibody, PLANH1 antibody, SERPINE1 antibody, si:ch211-138a11.1 antibody, Planh1 antibody, PAI1A antibody, Pai1 antibody, Pai1aa antibody, Planh antibody, RATPAI1A antibody, serpin family E member 1 antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antibody, serine (or cysteine) peptidase inhibitor, clade E, member 1 antibody, SERPINE1 antibody, serpine1.L antibody, serpine1 antibody, Serpine1 antibody
    背景
    PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1
    分子量
    45.1 kDa (NP_000593.1)
    NCBI登录号
    NM_000602
    UniProt
    P05121
    途径
    p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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