CARD6 抗体 (N-Term)
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Quick Overview for CARD6 抗体 (N-Term) (ABIN374318)
抗原
See all CARD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ATESTPSEII ERER-C
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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免疫原
- Peptide from N Terminus of the protein sequence according to NP_115976.2 Genename: CARD6
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anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 755-787) antibody
CARD6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23118 unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 1-110) antibodyCARD6 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 666-930) antibodyCARD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (AA 1-50) antibodyCARD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyVerified CARD6 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 6 (CARD6) (N-Term) antibodyCARD6 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Peptide ELISA: Limit dilution 1: 32000. Western blot: Approx.45-50 kDa and 25-30 kDa bands observed in A549, Human Heart andHuman Skeletal Muscle lysates at 1 μg of primary. Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Pancreas shows variable
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- CARD6 (Caspase Recruitment Domain Family, Member 6 (CARD6))
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别名
- CARD6
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背景
- CARDs (caspase recruitment domain) are homotypic protein-protein interaction motifs belonging to the death domain (DD)-fold superfamily (reviewed in Werts et al, 2006). Homotypic interactions among CARD-containing proteins can occur with various proteins, including the inactive zymogen forms of caspases which have N-terminal pro-domains containing complementary CARDs. These interactions can result in the formation of multiprotein complexes, leading to protease cleavage and caspase activation. Most proteins containing a CARD are involved in signal transduction pathways that regulate apoptosis, adaptive immunity, or innate immunity including NF-kB activation and inflammation. There is a large number of CARD containing proteins, and the unique function of each remains to be fully elucidated. CARD6 is a CARD-containing protein with a domain structure that does not appear to be shared by any other protein (Stehlik et al, 2003). CARD6 has been found to associate with microtubules, and is structurally and potentially functionally related to the superfamily of interferon (INF)-inducible GTPases (Dufner, 2006). INF-inducible GTPases belong to a growing family of host defense proteins that confer cell immunity. Specifically, is thought that CARD6 may act as a pattern recognition receptor that combats pathogens in a cell-autonomous manner.Synonyms: Caspase recruitment domain-containing protein 6
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基因ID
- 84674
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NCBI登录号
- NP_115976
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UniProt
- Q9BX69
抗原
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