IRF5 抗体 (C-Term)
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Quick Overview for IRF5 抗体 (C-Term) (ABIN374255)
抗原
See all IRF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QGPWPMHPAG MQ
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特异性
- This antibody is expected to recognize all four reported isoforms.
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交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Cow.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide from C Terminus of the protein sequence according to NP_002191.1, NP_116032.1, NP_001092097.1, NP_001092099.1. Genename: IRF5
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anti-Interferon Regulatory Factor 5 (IRF5) (AA 395-504) antibody
IRF5 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (C-Term) antibodyVerified IRF5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 395-504) antibodyIRF5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 81-108) antibodyIRF5 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 1-200) antibodyIRF5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 214-395) antibodyIRF5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) antibodyIRF5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 176-240) antibodyIRF5 适用: 人 WB, ELISA, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 10T1 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) (AA 1-498) antibodyIRF5 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Interferon Regulatory Factor 5 (IRF5) antibodyIRF5 适用: 人 WB, IHC (p) 宿主: 兔 Monoclonal 3F11 unconjugated
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应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.1-0.3 μg/mL. Approx 57 kDa band observed in lysates of cell line A549. Intransfected HEK293 transiently expressing IRF5 a strong band of approx.67 kDa isobserved. This band is not observed in the non-transfected HEK293.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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别名
- IRF5
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背景
- Interferon regulatory factors (IRFs) are transcription factors that possess a novel helix turn helix DNA binding motif and mediate virus and interferon (IFN) induced signaling pathways. The IRF5 protein is structurally related to IRF6. Like other IRFs, IRF5 and IRF6 contain 5 conserved tryptophan residues in the 115 amino acid N terminal DNA binding domain. IRF5 has a central IRF association domain (IAD) and, like IRF7 and IRF8, is induced by IFNA/IFNB stimulation. IRF5 has a type I IFN transactivation potential similar to that of IRF1. IRF3 and IRF5 form heterodimers and are both required for effective induction of IFNA gene transcription.Synonyms: IRF-5, Interferon regulatory factor 5
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基因ID
- 3663
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NCBI登录号
- NP_002191
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UniProt
- Q13568
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途径
- TLR signaling, Autophagy
抗原
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