JUP 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for JUP 抗体 (C-Term) (ABIN374233)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- C-GLRPPYPTAD HMLA
-
特异性
- This antibody detects Junction plakoglobin at C-term. This antibody is expected to recognise both reported isoforms (NP_002221.1 and NP_068831.1).
-
交叉反应 (详细)
-
Species reactivity (expected):Mouse, Canine (Dog), Pig.
Species reactivity (tested):Human, Rat. -
纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
-
免疫原
- Peptide from C Terminus of the protein sequence according to NP_002221.1, NP_068831.1 Genename: JUP
-
-
-
-
应用备注
-
Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.2-1 μg/mL. Approx 85 kDa band observed in A431 lysate (predicted MW of85 kDa according to NP_002221, NP_068831).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- JUP (Junction Plakoglobin (JUP))
-
别名
- Junction Plakoglobin
-
背景
- Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.Synonyms: CTNNG, Catenin gamma, DP3, Desmoplakin III, Desmoplakin-3, JUP
-
基因ID
- 3728
-
NCBI登录号
- NP_002221
-
UniProt
- P14923
-
途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
-