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CSK 抗体 (C-Term)

CSK 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374096
发货至: 中国
  • 抗原 See all CSK 抗体
    CSK (C-Src tyrosine Kinase (CSK))
    抗原表位
    • 19
    • 16
    • 12
    • 11
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 112
    • 57
    • 45
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 100
    • 11
    • 3
    山羊
    克隆类型
    • 100
    • 13
    多克隆
    标记
    • 54
    • 9
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This CSK antibody is un-conjugated
    应用范围
    • 102
    • 49
    • 26
    • 26
    • 16
    • 15
    • 13
    • 9
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-EQLEHIKTHE LHL
    特异性
    This antibody detects Tyrosine-Protein Kinase CSK at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Cow.
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide from the C Terminus of the protein sequence according to NP_004374.1, NP_001120662.1 Genename: 1445
    Top Product
    Discover our top product CSK Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 50 kDa band observed in Jurkat lysate (predicted MW of50.0 kDa according to NP_004374.1). Immunohistochemistry: 0.1-0.3 μg/mL. In paraffin embedded human tonsil, strong stainingof germinal centre cells and less intense labelling in the interfollicular area.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CSK (C-Src tyrosine Kinase (CSK))
    别名
    CSK (CSK 产品)
    别名
    AW212630 antibody, C-terminal Src kinase antibody, c-src tyrosine kinase antibody, CSK, non-receptor tyrosine kinase antibody, CSK antibody, Csk antibody
    背景
    C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).Synonyms: C-SRC kinase, Protein-tyrosine kinase CYL, Tyrosine-protein kinase CSK
    基因ID
    1445
    NCBI登录号
    NP_004374
    UniProt
    P41240
    途径
    TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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