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MAPT 抗体 (pSer416)

Name: MAPT 抗体 (pSer416)
SKU: ABIN372727
Availability: OutOfStock

MAPT 适用: 人, 小鼠, 大鼠, Cow, 犬, Non-Human Primate WB 宿主: 兔 Polyclonal unconjugated

Image no. 1 for anti-Microtubule-Associated Protein tau (MAPT) (pSer416) antibody (ABIN372727) (MAPT 抗体 (pSer416))

1 image

产品编号 ABIN372727

发货至: 中国

Datasheet as PDF

抗原 See all MAPT 抗体

MAPT (Microtubule-Associated Protein tau (MAPT))
抗原表位
10

9

8

8

7

6

6

6

6

6

5

5

5

5

5

5

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
pSer416
适用
210

109

99

13

12

7

7

6

4

3

2

2

2

1

1
人, 小鼠, 大鼠, Cow, 犬, Non-Human Primate
宿主
197

17

6
兔
Compatible Secondaries
克隆类型
194

26
多克隆
标记
174

17

6

5

2

2

2

2

2

2

2

2

1

1
This MAPT antibody is un-conjugated
应用范围
190

119

61

34

22

20

12

3

2

2

2

1

1
Western Blotting (WB)

特异性

Specific for ~59, 65, 68k Tau protein phosphorylated at Ser416.

交叉反应（详细）

Species reactivity (expected):Human, Bovine, Canine, Mouse and non-Human Primates.
Species reactivity (tested):Rat.

纯化方法

Affinity Chromatography via sequential chromatography on phospho- and dephospho-peptide affinity columns

免疫原

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser416 of Rat MAPT/TAU.

亚型

IgG

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anti-Microtubule-Associated Protein tau (MAPT) (AA 1-100) antibody
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anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
MAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibody
MAPT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

缓冲液

10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store the antibody undiluted (in aliquots) at-20 °C.
抗原

MAPT (Microtubule-Associated Protein tau (MAPT))

别名

MAPT / tau (MAPT 产品)

别名

DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody

背景

Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy. It has been well documented that hyperphosphorylated tau is a major component of paired helical filaments in AD brain (Lee 1995). Serine 416 has been demonstrated to be a major phosphorylation site in vitro by CaM kinase II (Steiner at al. 1990).Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau

基因ID

10116

UniProt

P19332

途径

MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size