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TAO Kinase 2 抗体 (pSer181)

TAOK2 适用: 人, 小鼠, 大鼠, 犬, 非洲爪蟾, 斑马鱼, Finch WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372726
发货至: 中国
  • 抗原 See all TAO Kinase 2 (TAOK2) 抗体
    TAO Kinase 2 (TAOK2)
    抗原表位
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    pSer181
    适用
    人, 小鼠, 大鼠, 犬, 非洲爪蟾, 斑马鱼, Finch
    宿主
    • 33
    • 2
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TAO Kinase 2 antibody is un-conjugated
    应用范围
    • 23
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
    交叉反应 (详细)
    Species reactivity (expected):Canine, Finch, Xenopus and Zebrafish.
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Affinity Chromatography via sequential chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser181 of TAO2.
    亚型
    IgG
    Top Product
    Discover our top product TAOK2 Primary Antibody
  • 应用备注
    Western blot: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    TAO Kinase 2 (TAOK2)
    Abstract
    TAOK2 产品
    背景
    In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.Synonyms: KFC-C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, UNQ2971/PRO7431
    基因ID
    9344
    NCBI登录号
    NP_004774
    UniProt
    Q9UL54
    途径
    Cell-Cell Junction Organization
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