TAO Kinase 2 抗体 (pSer181)
Quick Overview for TAO Kinase 2 抗体 (pSer181) (ABIN372726)
抗原
See all TAO Kinase 2 (TAOK2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer181
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特异性
- Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
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交叉反应 （详细）
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Species reactivity (expected):Canine, Finch, Xenopus and Zebrafish.
Species reactivity (tested):Human, Mouse and Rat. -
纯化方法
- Affinity Chromatography via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser181 of TAO2.
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亚型
- IgG
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anti-TAO Kinase 2 (TAOK2) (AA 831-930) antibody
TAOK2 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-TAO Kinase 2 (TAOK2) (pSer181) antibodyTAOK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TAO Kinase 2 (TAOK2) (AA 831-930) antibodyTAOK2 适用: 人 ELISA, WB, IF, PLA 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-TAO Kinase 2 (TAOK2) (AA 719-880) antibodyTAOK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAO Kinase 2 (TAOK2) (pSer181) antibodyTAOK2 适用: 人, 小鼠, 大鼠, 犬, 非洲爪蟾 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAO Kinase 2 (TAOK2) (AA 610-730) antibodyTAOK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- TAO Kinase 2 (TAOK2)
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背景
- In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.Synonyms: KFC-C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, UNQ2971/PRO7431
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基因ID
- 9344
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NCBI登录号
- NP_004774
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UniProt
- Q9UL54
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途径
- Cell-Cell Junction Organization
抗原
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