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SYN1 抗体 (pSer549)

SYN1 适用: 人, 小鼠, 大鼠, Cow, 犬, Non-Human Primate WB, IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372720
发货至: 中国
  • 抗原 See all SYN1 抗体
    SYN1 (Synapsin I (SYN1))
    抗原表位
    • 26
    • 15
    • 14
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer549
    适用
    • 116
    • 94
    • 75
    • 15
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow, 犬, Non-Human Primate
    宿主
    • 122
    • 7
    克隆类型
    • 115
    • 14
    多克隆
    标记
    • 75
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYN1 antibody is un-conjugated
    应用范围
    • 86
    • 44
    • 31
    • 20
    • 15
    • 13
    • 13
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)
    特异性
    This antibody recognizes the ~78k Synapsin I doublet protein phosphorylated at Ser549. Immunolabeling of the synapsin I band is blocked by lambda-phosphatase treatment.
    交叉反应 (详细)
    Species reactivity (expected):Human, Bovine, Canine, Mouse and non-Human Primates.
    Species reactivity (tested):Rat.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser549 of Synapsin I.
    亚型
    IgG
    Top Product
    Discover our top product SYN1 Primary Antibody
  • 应用备注
    Western blot: 1/1,000. Immunohistochemistry: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    SYN1 (Synapsin I (SYN1))
    别名
    Synapsin-1 (SYN1 产品)
    别名
    SYN1a antibody, SYN1b antibody, SYNI antibody, Syn-1 antibody, SYN I antibody, si:dkey-90n12.3 antibody, synapsin I antibody, synapsin I L homeolog antibody, SYN1 antibody, Syn1 antibody, syn1.L antibody, syn1 antibody
    背景
    Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.Synonyms: Brain protein 4.1, SYN1, Synapsin I
    基因ID
    6853
    NCBI登录号
    NP_008881
    UniProt
    P17600
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