Periostin 抗体
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北京 101111
Quick Overview for Periostin 抗体 (ABIN372701)
抗原
See all Periostin (POSTN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes the three Periostin bands around ~93 kDa in Mouse lung extract. The immunogenic peptide is present in all known splice variants of Periostin and therefore this antibody recognizes all known molecular forms of Periostin.
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交叉反应 (详细)
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Species reactivity (expected):Mammalia, Birds, Amphibians and Fishes.
Species reactivity (tested):Human, Chicken, Mouse and Rat. -
纯化方法
- Affinity Chromatography.
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免疫原
- Peptide from fasciclin domain 1 of Mouse Periostin.
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亚型
- IgG
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应用备注
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Western blot: 1/1000. Immunohistochemistry: 1/100. Immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrievalprotocol (incubate slides for 20 minutes at 90 °C in 10 mM sodium citrate ( pH 6.0)/ 0.1 % Tween-20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C. For long term store the antibody (in aliquots) at -80 °C.
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- Periostin (POSTN)
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别名
- Periostin
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背景
- Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008)Synonyms: OSF-2, OSF2, Osteoblast-specific factor 2, PN, POSTN
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基因ID
- 10631
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NCBI登录号
- NP_001129406
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UniProt
- Q15063
抗原
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