Periostin 抗体 (C-Term)
Quick Overview for Periostin 抗体 (C-Term) (ABIN372700)
抗原
See all Periostin (POSTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody recognizes the ~93 kDa Periostin doublet in mouse lung extract. This antibody does not recognize the single heart form of Periostin or the lowest molecular weight form of lung periostin. Consistent with the fact that this antibody is made against an alternatively spliced region of periostin, this antibody recognizes a subset of the forms of Periostin recognized on Western blots by the Pan Periostin antibody (Cat#AP08724AF-N) and also shows a distinctive staining pattern by Immunohistochemistry (data not shown).
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交叉反应 （详细）
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Species reactivity (expected):Mammalia and Avian.
Species reactivity (tested):Human, Mouse, Rat and Chicken. -
纯化方法
- Affinity Chromatography.
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免疫原
- Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse Periostin which is comprised of six small alternatively-spliced exons.
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亚型
- IgG
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anti-Periostin (POSTN) (C-Term) antibody
POSTN 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 97-230) antibodyPOSTN 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 577-810) antibodyPOSTN 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 687-716), (C-Term) antibodyPOSTN 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18585 unconjugated
anti-Periostin (POSTN) (Middle Region) antibodyPOSTN 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Cow, 犬, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 24-836) antibodyPOSTN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 24-173) antibodyPOSTN 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-649M unconjugated
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应用备注
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Western blot: 1/1000. Immunohistochemistry: 1/100. The antibody works well for Immunohistochemistry on paraformaldehyde-fixed sectionswith a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90 °C in 10 mMsodium citrate ( pH 6.0)/ 0.1 % Tween-20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Periostin (POSTN)
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别名
- Periostin
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背景
- Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008)Synonyms: OSF-2, OSF2, Osteoblast-specific factor 2, PN, POSTN
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基因ID
- 10631
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NCBI登录号
- NP_001129406
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UniProt
- Q15063
抗原
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