HSD11B2 抗体 (AA 25-40)
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- 抗原 See all HSD11B2 抗体
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
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抗原表位
- AA 25-40
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD11B2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 序列
- R25SDLRLGRPLL AALAL4
- 特异性
- This antibody recognizes 11-HSD2.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide corresponding to amino acids 25-40 of human 11 beta-HSD2.
- 亚型
- IgG
- Top Product
- Discover our top product HSD11B2 Primary Antibody
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anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 151-250) antibody
HSD11B2 适用: 大鼠, 小鼠, 马 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) antibodyHSD11B2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) antibodyHSD11B2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 277-309), (C-Term) antibodyHSD11B2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (N-Term) antibodyHSD11B2 适用: 人, 大鼠, 小鼠, 马, 豚鼠, 兔, 绵羊, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 212-343) antibodyHSD11B2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) antibodyHSD11B2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) antibodyHSD11B2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 277-306) antibodyHSD11B2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24535 unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 284-314), (Middle Region) antibodyHSD11B2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1/200. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- TBS, pH 7.4 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA, 50 % Glycerol as stabilizers.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
- 别名
- 11-beta HSD2 / HSD11B2 (HSD11B2 产品)
- 别名
- MGC81883 antibody, 11-HSD2 antibody, AME antibody, AME1 antibody, HSD11K antibody, HSD2 antibody, SDR9C3 antibody, 11HSD2 antibody, HSD11B2 antibody, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antibody, hydroxysteroid 11-beta dehydrogenase 2 antibody, hsd11b2.L antibody, HSD11B2 antibody, Hsd11b2 antibody
- 背景
- HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. The protein modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME). AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.Synonyms: 11-DH2, 11-beta-hydroxysteroid dehydrogenase 2, Corticosteroid 11-beta-dehydrogenase isozyme 2, HSD11K, NAD-dependent 11-beta-hydroxysteroid dehydrogenase
- 基因ID
- 3291
- NCBI登录号
- NP_000187
- UniProt
- P80365
- 途径
- Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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