XPO1 抗体 (AA 390-408)
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- 抗原 See all XPO1 抗体
- XPO1 (Exportin 1 (XPO1))
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抗原表位
- AA 390-408
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Chimpanzee
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XPO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 序列
- ASPLLSGSQH FDVPPRRQL
- 特异性
- This antibody recognizes CRM1 Protein (XPO1).
- 交叉反应 （详细）
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Species reactivity (expected):Bovine, Chimpanzee, Dog, Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Protein G Chromatography.
- 免疫原
- Synthetic peptide corresponding to the amino acids 390-408 of human Exportin-1 protein.
- 亚型
- IgG
- Top Product
- Discover our top product XPO1 Primary Antibody
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anti-Exportin 1 (XPO1) (AA 966-1071) antibody
XPO1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 625-845) antibodyXPO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (C-Term) antibodyXPO1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, Pig, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 701-800) antibodyXPO1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 917-1071) antibodyXPO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9F2 unconjugated Recombinant Antibody
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 966-1071) antibodyXPO1 适用: 人 WB, IHC (p), FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 5G3 unconjugated
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- 应用备注
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Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- XPO1 (Exportin 1 (XPO1))
- 别名
- XPO1 / Exportin-1 (XPO1 产品)
- 别名
- CG13387 antibody, CRM1 antibody, Crm1 antibody, DCRM1 antibody, Dmel\\CG13387 antibody, Emb antibody, XPO-1 antibody, XPO1 antibody, Xpo1 antibody, crm1 antibody, dCRM1 antibody, l(2)k16715 antibody, 18.m06600 antibody, DDBDRAFT_0183812 antibody, DDBDRAFT_0234066 antibody, DDB_0183812 antibody, DDB_0234066 antibody, exportin-1 antibody, LOC100220104 antibody, emb antibody, exp1 antibody, Xpo antibody, AA420417 antibody, Exp1 antibody, embargoed antibody, exportin 1 antibody, putative exportin 1 antibody, chromosome region maintenance protein 1 antibody, exportin-1 antibody, exportin 1 (CRM1 homolog, yeast) antibody, exportin 1 S homeolog antibody, emb antibody, cgd3_3060 antibody, Tc00.1047053511725.150 antibody, Tb11.01.5940 antibody, BBOV_II007220 antibody, LMJF_32_1100 antibody, xpo1 antibody, Xpo1 antibody, XPO1 antibody, LOC100165622 antibody, LOC100633509 antibody, xpo1.S antibody
- 背景
- CRM1 (chromosome region maintenance 1 protein homolog) mediates the nuclear export of cellular proteins (cargoes) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, CRM1 binds cooperatively to the NES on its target protein and to the GTPase Ran in its active GTP-bound form. Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The direction of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. CRM1 also mediates the nuclear export of the Rev protein of HIV-1 and Rex protein of HTLV-1. It is involved in Rex dimerization, U3 snoRNA transport from Cajal bodies to nucleoli. CRM1 is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. CRM1 is also involved in the regulation NFAT and AP-1.Synonyms: CRM1, Chromosome region maintenance 1 protein homolog, Exp1
- 基因ID
- 7514
- NCBI登录号
- NP_003391
- UniProt
- O14980
- 途径
- M Phase
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