LAMP2 抗体 (Biotin)
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- 抗原 See all LAMP2 抗体
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LAMP2 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognizes CD107b/LAMP-2.
- 产品特性
- Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
- 克隆位点
- H4B4
- 亚型
- IgG1
- Top Product
- Discover our top product LAMP2 Primary Antibody
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- 应用备注
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Flow Cytometry: 10 μL/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- 别名
- CD107b / LAMP2 (LAMP2 产品)
- 背景
- CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107b is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-2 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium. (Ref.1-7)Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
- 基因ID
- 3920
- UniProt
- P13473
- 途径
- Autophagy
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